Person
ISNI: 
0000 0001 2278 2099
https://isni.org/isni/0000000122782099
Name: 
Eric Kandel (American neuropsychiatrist)
Eric Kandel (Amerikaans neuroloog)
Eric Kandel (amerikanischer Neurowissenschaftler, Nobelpreisträger)
Eric Kandel (neurobiolog amerykański, noblista)
Eric Kandel (neurologo, psichiatra e neuroscienziato statunitense)
Eric R. Kandel
Eric Richard Kandel
Eriks Kandels
Kandel, E. R.
Kandel (E. R.; 1929-)
Kandel, Eric
Kandel, Eric R.
Kandel, Eric Richard
Kandel, Erich R.
Kendel, E.
Ерик Кандел
Ерік Кендел
Кандел, Эрик (Американский психиатр и биохимик, лауреат Нобелевской премии)
Кандель, Э. Р
Кандель, Эрик Р.
Кэндел (Э. Р; 1929-)
Эрик Кандел
Эрык Кэндэл
Էրիկ Կանդել
אריק קנדל
إريك آر. كاندل،
إريك كاندل
ارک کینڈل
اریک کندل
ایرک کینڈل
كاندل، إريك آر.،
كاندل، إيرك آر.،
எரிக் காண்டல்
എറിക് കാൻഡൽ
エリック・カンデル
カンデル, エリック・R.
埃里克·坎德尔
Dates: 
1929-
Creation class: 
article
Language material
Projected medium
txt
Creation role: 
author
creator
editor
redactor
Related names: 
Calissano, Pietro Levi
Desgranges, Béatrice
Desgranges, Béatrice (1955-...)
Eustache, Francis (1955-...)
Jessell, Thomas M.
Kandel, Eric Richard
Levi Montalcini, Rita
Mack, Sarah
Mountcastle, Vernon B.
Schwartz, James H.
Schwartz, James H. (1932-2006)
Schwartz, James Harris
Schwartz, James Harris (1932-2006)
Squire, Larry R.
Squire, Larry Ryan (1941-....))
Wiese, Martina
عرار، سامر
桐野, 豊 (1944-)
Titles: 
1987 cell-biological interrelationships between short-term and long-term memory.
5-Hydroxytryptamine Induces a Protein Kinase A/Mitogen-Activated Protein Kinase-Mediated and Macromolecular Synthesis-Dependent Late Phase of Long-Term Potentiation in the Amygdala
À la recherche de la mémoire
Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus
Abolition of long-term stability of new hippocampal place cell maps by NMDA receptor blockade.
Abstracts of papers presented at the 1990 meeting on cell and molecular neurobiology of aplysia, 1990:
Activation of a heterologously expressed octopamine receptor coupled only to adenylyl cyclase produces all the features of presynaptic facilitation in Aplysia sensory neurons
Activity-dependent long-term enhancement of transmitter release by presynaptic 3',5'-cyclic GMP in cultured hippocampal neurons
Activity-dependent presynaptic facilitation and hebbian LTP are both required and interact during classical conditioning in Aplysia.
Age of insight the quest to understand the unconscious in art, mind, and brain : from vienna 1900 to the present
Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway.
Altered Hippocampal Transcript Profile Accompanies an Age-Related Spatial Memory Deficit in Mice
Animal Model of a Behavioral Intervention for Depression, An
Annu. rev. neurosci. (Print)
Annual review of neuroscience
Aplysia CPEB Can Form Prion-like Multimers in Sensory Neurons that Contribute to Long-Term Facilitation
Aplysia CREB2 represses long-term facilitation: relief of repression converts transient facilitation into long-term functional and structural change.
Article: Transgenic Mice Lacking NMDAR-Dependent LTD Exhibit Deficits in Behavioral Flexibility
Attention enhances the retrieval and stability of visuospatial and olfactory representations in the dorsal hippocampus.
Auf der Suche nach dem Gedächtnis die Entstehung einer neuen Wissenschaft des Geistes
Augmentation prolongée de l'efficacité d'une voie afférente d'un ganglion isolé après l'activation couplée d'une voie plus efficace...
Axonal transport of eukaryotic translation elongation factor 1 alpha mRNA couples transcription in the nucleus to long-term facilitation at the synapse
Axonal transport of eukaryotic translation elongation factor 1alpha mRNA couples transcription in the nucleus to long-term facilitation at the synapse.
Behavioral biology of Aplysia a contribution to the comparative study of opisthobranch molluscs
Behavioral Role for Dendritic Integration HCN1 Channels Constrain Spatial Memory and Plasticity at Inputs to Distal Dendrites of CA1 Pyramidal Neurons, A
Bidirectional regulation of hippocampal long-term synaptic plasticity and its influence on opposing forms of memory.
biology of memory: a forty-year perspective., The
Biology of Memory, The : A Forty-Year Perspective
Both Protein Kinase A and Mitogen-Activated Protein Kinase Are Required in the Amygdala for the Macromolecular Synthesis-Dependent Late Phase of Long-Term Potentiation
Brief theta -burst stimulation induces a transcription-dependent late phase of LTP requiring cAMP in area CA1 of the mouse hippocampus
Calcineurin-Mediated LTD of GABAergic Inhibition Underlies the Increased Excitability of CA1 Neurons Associated with LTP
cAMP Response Element-Binding Protein-Mediated Gene Expression Increases the Intrinsic Excitability of CA1 Pyramidal Neurons
Capture of a protein synthesis-dependent component of long-term depression.
Capture of the Late Phase of Long-Term Potentiation within and across the Apical and Basilar Dendritic Compartments of CA1 Pyramidal Neurons: Synaptic Tagging Is Compartment Restricted
Cell adhesion molecules, CREB, and the formation of new synaptic connections.
cell-biological approach to learning, A
Cellular basis of behavior : an introduction to behavioral neurobiology
Cellular mechanisms in the selection and modulation of behavior
Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.
Chronic Enhancement of CREB Activity in the Hippocampus Interferes with the Retrieval of Spatial Information
Chronic Nicotine Exposure Induces a Long-Lasting and Pathway-Specific Facilitation of LTP in the Amygdala
Chronically increased G sub(s) alpha signaling disrupts associative and spatial learning
Chronically Increased G[subscript s][alpha] Signaling Disrupts Associative and Spatial Learning
Chronically increased Gsalpha signaling disrupts associative and spatial learning.
Classical conditioning, differential conditioning, and second-order conditioning of the Aplysia gill-withdrawal reflex in a simplified mantle organ preparation.
Classical conditioning of the Aplysia siphon-withdrawal reflex exhibits response specificity.
Cognitive Neuroscience and the Study of Memory
Common molecular mechanisms in explicit and implicit memory.
Confocal imaging of cAMP signals in Aplysia neurons.
Contribution of Activity-Dependent Synaptic Plasticity to Classical Conditioning in Aplysia, The
CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum
CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects.
Cyclic AMP induces functional presynaptic boutons in hippocampal CA3-CA1 neuronal cultures
D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex
Differential evolutionary rates of neuronal transcriptome in Aplysia kurodai and Aplysia californica as a tool for gene mining.
Dishabituation in Aplysia can involve either reversal of habituation or superimposed sensitization
DRD2 C957T polymorphism interacts with the COMT Val158Met polymorphism in human working memory ability.
Dscam mediates remodeling of glutamate receptors in Aplysia during de novo and learning-related synapse formation.
emergence of modern neuroscience: some implications for neurology and psychiatry., The
En busca de la memoria : el nacimiento de una nueva ciencia de la mente
Enhancement of Memory-Related Long-Term Facilitation by ApAF, a Novel Transcription Factor that Acts Downstream from Both CREB1 and CREB2
Era del inconsciente, La : la exploración del inconsciente en el arte, la mente y el cerebro
ERK Plays a Regulatory Role in Induction of LTP by Theta Frequency Stimulation and Its Modulation by beta -Adrenergic Receptors
Essentials Neural Science Text Study Guide Package
Essentials of neural science and behavior
Evidence for synaptotagmin as an inhibitory clamp on synaptic vesicle release in Aplysia neurons
Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic capture.
Eye to i : 3,000 years of portraits
Fear conditioning occludes LTP-induced presynaptic enhancement of synaptic transmission in the cortical pathway to the lateral amygdala.
FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons.
form of long-lasting, learning-related synaptic plasticity in the hippocampus induced by heterosynaptic low-frequency pairing, A
Gedächtnis die Natur des Erinnerns
Geheugen : van moleculen tot geest
Gene Expression Profiling of Facilitated L-LTP in VP16-CREB Mice Reveals that BDNF Is Critical for the Maintenance of LTP and Its Synaptic Capture
Genes, nerve cells, and the remembrance of things past.
Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin
Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory
Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation.
Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors.
genetic switch for long-term memory, A
Handbook of physiology : a critical, comprehensive presentation of physiological knowledge and concepts
Hirnforscher Erich Kandel
Huntingtin is critical both pre- and postsynaptically for long-term learning-related synaptic plasticity in Aplysia
hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells., The
Identification of a serotonin receptor coupled to adenylyl cyclase involved in learning-related heterosynaptic facilitation in Aplysia
Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear.
Imaging physiologic dysfunction of individual hippocampal subregions in humans and genetically modified mice.
Impaired Bidirectional Synaptic Plasticity and Procedural Memory Formation in Striatum-Specific cAMP Response Element-Binding Protein-Deficient Mice
Impaired Timing Precision Produced by Striatal D2 Receptor Overexpression Is Mediated by Cognitive and Motivational Deficits
Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency
In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus.
In search of memory the emergence of a new science of mind
In search of memory возникновение новой науки о человеческой психике
Increased attention to spatial context increases both place field stability and spatial memory.
Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces.
Inducible and reversible enhancement of learning, memory, and long-term potentiation by genetic inhibition of calcineurin.
Inducible and Reversible Gene Expression with the rtTA System for the Study of Memory
Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins.
Input-specific synaptic plasticity in the amygdala is regulated by neuroligin-1 via postsynaptic NMDA receptors
Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure.
Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to Eag and cyclic nucleotide-gated channels
introduction to the work of David Hubel and Torsten Wiesel., An
Is heterosynaptic modulation essential for stabilizing Hebbian plasticity and memory?
Kioku no shikumi.
Kletočnyje osnovy povedenija
LABORATORY OF NEUROBIOLOGY--NEURONAL CONTROL OF MUSCLE ACTION
Learning and memory : a subject collection from cold spring harbor perspectives in biology
Learning-Related Synaptic Growth Mediated by Internalization of Aplysia Cell Adhesion Molecule Is Controlled by Membrane Phosphatidylinositol 4,5-Bisphosphate Synthetic Pathway
Life in death still lifes and select masterworks of Chaim Soutine : [exhibition], Paul Kasmin gallery, New York, April 24 - June 14, 2014]
Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells.
Local protein synthesis and its role in synapse-specific plasticity.
long-term stability of new hippocampal place fields requires new protein synthesis, The
Low-frequency stimulation induces a pathway-specific late phase of LTP in the amygdala that is mediated by PKA and dependent on protein synthesis.
macromolecular synthesis-dependent late phase of long-term potentiation requiring cAMP in the medial perforant pathway of rat hippocampal slices., A
MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia
Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia.
mémoire, La : de l'esprit aux molécules
Memória da mente às moléculas
Memory and behavior: A second generation of genetically modified mice
Memory : from mind to molecules
Memory suppressor genes: Inhibitory constraints on the storage of long-term memory
Michael V.L. Bennett and the cellular study of neural systems at Albert Einstein and Woods Hole.
Modeling cognitive endophenotypes of schizophrenia in mice.
Modeling motivational deficits in mouse models of schizophrenia: behavior analysis as a guide for neuroscience.
Molecular aspects of neurobiology
molecular biology of memory storage: a dialog between genes and synapses., The
molecular biology of memory storage: a dialogue between genes and synapses., The
Molecular Biology of Memory Storage, The : A Dialog Between Genes and Synapses
molecular biology of memory storage, The : a dialogue between genes and synapses
Molecular Mechanisms of Memory Storage in Aplysia
Molecular neurobiology in neurology and psychiatry
Mouse VAP33 is associated with the endoplasmic reticulum and microtubules
Mutation in the phosphorylation sites of MAP kinase blocks learning-related internalization of apCAM in Aplysia sensory neurons.
n79132454
Nervous system., The
Neural science: a century of progress and the mysteries that remain.
Neurexin-neuroligin transsynaptic interaction mediates learning-related synaptic remodeling and long-term facilitation in aplysia.
Neurociencia y conducta
Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals
neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia., A
neuronal isoform of the aplysia CPEB has prion-like properties., A
Neuronal transcriptome of Aplysia: neuronal compartments and circuitry.
Neurowissenschaften eine Einführung
New Component in Synaptic Plasticity: Upregulation of Kinesin in the Neurons of the Gill-Withdrawal Reflex, A
Nitric oxide acts directly in the presynaptic neuron to produce long-term potentiation in cultured hippocampal neurons.
Nitric oxide and carbon monoxide produce activity-dependent long-term synaptic enhancement in hippocampus.
Nitric oxide and cGMP can produce either synaptic depression or potentiation depending on the frequency of presynaptic stimulation in the hippocampus.
novel function for serotonin-mediated short-term facilitation in aplysia: conversion of a transient, cell-wide homosynaptic hebbian plasticity into a persistent, protein synthesis-independent synapse-specific enhancement., A
novel function for serotonin-mediated short-term facilitation in Aplysia: Conversion of a transient, cell-wide homosynpaptic Hebbian plasticity into a persistent, protein synthesis-independent..., A
Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia.
Obituary: James H. Schwartz
Österreichs Umgang mit dem Nationalsozialismus : die Folgen für die naturwissenschaftliche und humanistische Lehre : Internationales Symposium, 5.-6. Juni 2003, Wien
p38 MAP kinase mediates both short-term and long-term synaptic depression in aplysia.
Paradoxical influence of hippocampal neurogenesis on working memory
parallel between radical reductionism in science and in art., A
past, the future and the biology of memory storage., The
persistence of long-term memory: a molecular approach to self-sustaining changes in learning-induced synaptic growth., The
Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophrenia.
PKA-activated ApAF-ApC/EBP heterodimer is a key downstream effector of ApCREB and is necessary and sufficient for the consolidation of long-term facilitation
PLASTICITY OF THE SIMPLEST NEURONAL PATHWAYS
Positive and negative regulatory mechanisms that mediate long-term memory storage
Possible Role for the Striatum in the Pathogenesis of the Cognitive Symptoms of Schizophrenia, A
Postsynaptic Induction and PKA-Dependent Expression of LTP in the Lateral Amygdala
Presynaptic activation of silent synapses and growth of new synapses contribute to intermediate and long-term facilitation in Aplysia.
Presynaptic and postsynaptic mechanisms of synaptic plasticity and metaplasticity during intermediate-term memory formation in Aplysia.
Presynaptic and postsynaptic roles of NO, cGK, and RhoA in long-lasting potentiation and aggregation of synaptic proteins.
Presynaptic BDNF required for a presynaptic but not postsynaptic component of LTP at hippocampal CA1-CA3 synapses.
presynaptic locus for long-term potentiation of elementary synaptic transmission at mossy fiber synapses in culture, A
Presynaptic Role for FMRP during Protein Synthesis-Dependent Long-Term Plasticity in "Aplysia", A
Principles of neural science
Protein synthesis during acquisition of long-term facilitation is needed for the persistent loss of regulatory subunits of the Aplysia cAMP-dependent protein kinase.
Proteins functioning in synaptic transmission at the sensory to motor synapse of Aplysia
Psiquiatría, psicoanálisis, y la nueva biología de la mente
Psychiatrie, Psychoanalyse und die neue Biologie des Geistes
Psychiatry, psychoanalysis, and the new biology of mind
Radikalni redukcionizam : paralela u znanosti i umjetnosti
Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory.
Rapid increase in clusters of presynaptic proteins at onset of long-lasting potentiation
Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice.
Reconstitution of the hippocampal mossy fiber and associational-commissural pathways in a novel dissociated cell culture system.
Recruitment of new sites of synaptic transmission during the cAMP-dependent late phase of LTP at CA3-CA1 synapses in the hippocampus.
Reductionism in art and brain science : from figuration to abstraction of form, line, color, and light
Relationships between dishabituation, sensitization, and inhibition of the gill- and siphon-withdrawal reflex in Aplysia californica: effects of response measure, test time, and training stimulus.
Requirement of a critical period of transcription for induction of a late phase of LTP.
Resolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala
Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory.
Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory.
Reviews in Neuroscience: The molecular biology of memory storage: A dialogue between genes and synapses
Role in Learning for SRF: Deletion in the Adult Forebrain Disrupts LTD and the Formation of an Immediate Memory of a Novel Context, A
Role of "Aplysia" Cell Adhesion Molecules during 5-HT-Induced Long-Term Functional and Structural Changes
Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation.
Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory.
Selective Modulation of Some Forms of Schaffer Collateral-CA1 Synaptic Plasticity in Mice with a Disruption of the "CPEB-1" Gene
selective role of calcineurin aalpha in synaptic depotentiation in hippocampus., A
Serotonin-induced regulation of the actin network for learning-related synaptic growth requires Cdc42, N-WASP, and PAK in Aplysia sensory neurons.
Serotonin-mediated endocytosis of apCAM: an early step of learning-related synaptic growth in Aplysia.
Slide Set for Essentials of Neural Science
Some Forms of cAMP-Mediated Long-Lasting Potentiation Are Associated with Release of BDNF and Nuclear Translocation of Phospho-MAP Kinase
Spatially resolved dynamics of cAMP and protein kinase A subunits in Aplysia sensory neurons.
SPECIAL ISSUE REVIEW: Common molecular mechanisms in explicit and implicit memory
SPECIAL ISSUEREVIEW
Specific Role of cGMP in Hippocampal LTP, The
stathmin, a Gene Enriched in the Amygdala, Controls Both Learned and Innate Fear
Strain-dependent Differences in LTP and Hippocampus-dependent Memory in Inbred Mice
Sustained CPEB-dependent local protein synthesis is required to stabilize synaptic growth for persistence of long-term facilitation in Aplysia.
Synapse-specific, long-term facilitation of Aplysia sensory to motor synapses: A function for local protein synthesis in memory storage
Synaptically released zinc gates long-term potentiation in fear conditioning pathways
Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger.
Theta frequency stimulation up-regulates the synaptic strength of the pathway from CA1 to subiculum region of hippocampus
Tissue Plasminogen Activator Contributes to the Late Phase of LTP and to Synaptic Growth in the Hippocampal Mossy Fiber Pathway
Toward a molecular definition of long-term memory storage.
Toward a Neurobiology of Psychotherapy: Basic Science and Clinical Applications
Transcriptional regulation of long-term memory in the marine snail Aplysia.
Transcriptome analysis and identification of regulators for long-term plasticity in Aplysia kurodai
Transgenic approaches to cognition
Transgenic mice lacking NMDAR-dependent LTD exhibit deficits in behavioral flexibility.
Transient and selective overexpression of D^sub 2^ receptors in the striatum causes persistent deficits in conditional associative learning
Transient and selective overexpression of D₂ receptors in the striatum causes persistent deficits in conditional associative learning.
Transient and Selective Overexpression of Dopamine D2 Receptors in the Striatum Causes Persistent Abnormalities in Prefrontal Cortex Functioning
Transient expansion of synaptically connected dendritic spines upon induction of hippocampal long-term potentiation
Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis, A
Transient Overexpression of Striatal D sub(2) Receptors Impairs Operant Motivation and Interval Timing
Transient overexpression of striatal D2 receptors impairs operant motivation and interval timing.
Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus
Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia
unbiased cDNA library prepared from isolated Aplysia sensory neuron processes is enriched for cytoskeletal and translational mRNAs., An
Using an aplysia two-hybrid system to examine the interactions between transcription factors involved in long-term facilitation in the nervous system of aplysia.
VAMP-binding protein from Aplysia required for neurotransmitter release., A
What is remembered? Role of attention on the encoding and retrieval of hippocampal representations
Whereas Short-Term Facilitation Is Presynaptic, Intermediate-Term Facilitation Involves Both Presynaptic and Postsynaptic Protein Kinases and Protein Synthesis
Zeitalter der Erkenntnis die Erforschung des Unbewussten in Kunst, Geist und Gehirn von der Wiener Moderne bis heute
В поисках памяти
الذاكرة : من العقل الى الجزيئات
記憶のしくみ.
Contributed to or performed: 
BIOSCIENCE REPORTS
BRAIN RESEARCH REVIEWS
JOURNAL OF NEUROGENETICS
JOURNAL OF NEUROSCIENCE
JOURNAL OF PHYSIOLOGY -LONDON THEN CAMBRIDGE-
LEARNING AND MEMORY -NEW YORK-
MS -PARIS-
NEURON -CAMBRIDGE MA-
PROCEEDINGS- NATIONAL ACADEMY OF SCIENCES USA
Notes: 
Sources: 
VIAF VIAF VIAF BNC DNB EGAXA NDL NKC NLI NLR NSK NUKAT PTBNP SUDOC WKD
NLN
NLS
NTA
ZETO